一、个人简介：
李慧慧，博士，副教授，博/硕导。2018年于兰州大学获理学博士学位，同年加入海南大学“先进功能多孔材料”团队。在教学方面，主讲的课程有《分析化学》《仪器分析》《结构化学》等。在科研方面，主要从事荧光探针的构建与应用研究，在Anal. Chem.、Sensor. Actuat. B Chem.、Talanta、J. Hazard. Mater.、Food Chem.等国际权威学术期刊上发表SCI论文30余篇，申请发明专利3项，主持包括1项国家自然科学基金在内的各级各类项目6项。
二、科研项目：
（1）国家自然科学基金青年基金项目（C类），22004025，基于分子筛高效调控溶剂效应构建水相性能优异的D-π-A型荧光探针，2021-01至2023-12，24万元，主持。
（2）海南省自然科学基金高层次人才项目，122RC544，基于MOFs@ILs自组装材料的高灵敏四环素类抗生素荧光探针，2022-04至2025-03，10万元，主持。
（3）海南省自然科学基金青年基金项目，219QN154，“零背景结合信号放大”氟离子荧光传感系统的研究，2019-03至2021-12，5万元，主持。
（4）海南大学科研启动经费项目，KYQD(ZR)1926，MOF基H2O2比率荧光探针的构建与应用研究，2019-04至2023-10，100万元，主持。
（5）无机合成与制备化学国家重点实验室（吉林大学）开放课题，2024-19，分子筛/天然色素复合酸碱指示剂的制备及其在肉类新鲜度监测中的应用，2024-01至2025-12，3万元，主持。
（6）无机合成与制备化学国家重点实验室（吉林大学）开放课题，2020-28，MOF/苯乙烯菁主客体的构筑及其对BPO的比率荧光检测，2020-01至2021-12，3万元，主持。
三、代表性论著：
(1) Yu Li, Qinkun Huang, Huihui Li*, Shiyu Li, Jingxuan Han, Dong-Yu Guo*, Zhonglin Yu, Qinhe Pan*, Coordination-sensitized dual-channel fluorescence of a xylenol orange-based AIE complex for tetracycline detection in food, Dyes and Pigments, 2026, 248, 113579.（期刊论文）
(2) Yu Li, Kechun Yu, Huihui Li*， Shiyu Li, Jingxuan Han, Dong-Yu Guo*, Shengming Chen, Qinhe Pan*, Colorimetric xylenol orange: a long-buried aggregation-induced emission dye and restricted rotation for dual-mode sensing of pH
and metal ions, Analytical Chemistry, 2025, 97, 1845-1852.（期刊论文）
(3) Shengming Chen, Jingxuan Han, Huihui Li*, Shiyu Li, Yu Li, Dong-Yu Guo*, Shuqi Wang, Qinhe Pan*, Sensitive monitoring of meat freshness via changes in fluorescence intensity and wavelength based on protonation-regulated intramolecular charge transfer, Sensors and Actuators B: Chemical, 2025, 426, 137081.（期刊论文）
(4) Xi Chen, Wenhui Shi, Shiyu Li, Huihui Li*, Jingxuan Han, Dong-Yu Guo*, Linan Chen, Qinhe Pan*，In situ synthesis of luminescent dsDNA-Cu NCs stained with a dsDNA-lighted fluorophore for rapid and stable detection of histamine in food, International Journal of Biological Macromolecules, 2024, 277, 134479.（期刊论文）
(5) Yatian Cao, Xiaolong Gong, Le Li, Huihui Li*, Xuanming Zhang, Dong-Yu Guo*, Fuxiang Wang, Qinhe Pan*, Xylenol orange-modified CdTe quantum dots as a fluorescent/colorimetric dual-modal probe for anthrax biomarker based on competitive coordination, Talanta, 2023, 261, 124664.（期刊论文）
(6) Bo Fu, Jiakun Chen, Yatian Cao, Huihui Li*, Feng Gao, Dong-Yu Guo*, Fuxiang Wang, Qinhe Pan*, Post-modified metal-organic framework as ratiometric fluorescence-scattering probe for trace ciprofloxacin residue based on competitive coordination, Sensors and Actuators B: Chemical, 2022, 369, 132261.（期刊论文）
(7) Lu Ding, Yatan Cao, Huihui Li*, Fuxiang Wang, Dong-Yu Guo*, Weiting Yang, Qinhe Pan*, A ratiometric fluorescence-scattering sensor for rapid, sensitive and selective detection of doxycycline in animal foodstuffs, Food Chemistry, 2022, 373, 131669.（期刊论文）
(8) Lu Ding, Yanyu Zhao, Huihui Li*, Qiujuan Zhang, Weiting Yang*, Bo Fu, Qinhe Pan*, A highly selective ratiometric fluorescent probe for doxycycline based on the sensitization effect of bovine serum albumin, Journal of Hazardous Materials, 2021, 416, 125759.（期刊论文）
(9) Bo Fu, Xinyu Zheng, Huihui Li*, Lu Ding, Fuxiang Wang, Dong-Yu Guo*, Weiting Yang, Qinhe Pan*, A highly stable, rapid and sensitive fluorescent probe for ciprofloxacin based on Al3+-enhanced fluorescence of gold nanoclusters, Sensors and Actuators B: Chemical, 2021, 346, 130502.（期刊论文）
(10) Weikang Yang, Yonghang Yang, Huihui Li*, Duoyu Lin, Weiting Yang, Dongyu Guo*, Qinhe Pan*, Integration of Cd:ZnS QDs into ZIF-8 for enhanced selectivity toward Cu2+ detection, Inorganic Chemistry Frontiers, 2020, 7, 3718-3726.（期刊论文）
(11) Huihui Li, Fangxin Fu, Weiting Yang*, Lu Ding, Jiaxuan Dong, Yang Yang, Fuxiang Wang, Qinhe Pan*, A simple fluorescent probe for fast and sensitive detection of inorganic phosphate based on uranine@ZIF-8 composite, Sensors and Actuators B: Chemical, 2019, 301, 127110.（期刊论文）
(12) Huihui Li, Wei Liu, Fengyuan Zhang, Xinyue Zhu, Liqiu Huang, Haixia Zhang*, Highly selective fluorescent probe based on hydroxylation of phenylboronic acid pinacol ester for detection of tyrosinase in cells, Analytical Chemistry, 2018, 90, 855-858.（期刊论文）
(13) Huihui Li, Ling Zhu, Xinyue Zhu, Haixia Zhang*, Glucose detection via glucose-induced disaggregation of ammonium-modified tetraphenylethylene from polyanion, Sensors and Actuators B, 2017, 246, 819-825.（期刊论文）
(14) 李慧慧, 曹亚甜, 潘勤鹤, 炭疽杆菌孢子标志物荧光-紫外双模式检测方法, 2023-01-16, ZL202310062746.4.（授权发明专利）
(15) 张海霞, 李慧慧, 一种检测食品中果糖的方法, 2016-12-02, ZL201611095215.1.（授权发明专利）
